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Genetic matchmaking
Genetic Matchmaking is the idea of matching couples for romantic relationships based on their biological compatibility. The initial idea was conceptualized by Claus Wedekind through his famous "sweaty t-shirt" experiment.〔Wedekind, C., et al. "MHC-Dependent Mate Preferences in Humans." Proceedings.Biological sciences / The Royal Society 260.1359 (1995): 245-9.〕 Males were asked to wear T-shirts for two consecutive nights, and then females were asked to smell the t-shirts and rate the body odors for attractiveness. Human body odor has been associated with the human leukocyte antigens (HLA) genomic region. They discovered that females were attracted to men who had dissimilar HLA alleles from them. Furthermore, these females reported that the body odors of HLA-dissimilar males reminded them of their current partners or ex-partners providing further evidence of biological compatibility.
==Evidence of biological compatibility==
Following the seminal research done by Dr. Wedekind,〔 several studies found corroborating evidence for biological compatibility. Garver-Apgar ''et al.''〔Garver-Apgar, C. E., et al. "Major Histocompatibility Complex Alleles, Sexual Responsivity, and Unfaithfulness in Romantic Couples." Psychological science : a journal of the American Psychological Society / APS 17.10 (2006): 830-5.〕 presented evidence for HLA-dissimilar alleles playing a factor in the healthiness of romantic relationships. They discovered that as the proportion of HLA-similar alleles increased between couples, females reported being less sexually responsive to their partners, less satisfaction from being aroused by their partners, and having additional sexual partners (while with their current partner). Additionally, Ober ''et al.''〔Ober, C., et al. "HLA and Mate Choice in Humans." American Journal of Human Genetics 61.3 (1997): 497-504.〕 conducted an independent study on a population of American Hutterites by comparing the HLA alleles of married couples. They discovered that married couples were less likely to share HLA alleles than expected from random chance; thus their results were consistent with tendencies for same-HLA alleled partners to avoid mating. Further evidence of the importance of genetic compatibility can be found in the finding that couples sharing a higher proportion of HLA alleles tend to have recurring spontaneous abortions,〔Reznikoff-Etievant, M. F., et al. "HLA Antigen-Sharing in Couples with Repeated Spontaneous Abortions and the Birthweight of Babies in Successful Pregnancies." American journal of reproductive immunology (New York, N.Y.: 1989) 25.1 (1991): 25-7.〕 reduced body mass in babies,〔 and longer intervals between successive births.〔Ober, C., et al. "HLA Sharing and Fertility in Hutterite Couples: Evidence for Prenatal Selection Against Compatible Fetuses." American Journal of Reproductive Immunology and Microbiology : AJRIM 18.4 (1988): 111-5.〕
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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